Advances in Animal and Veterinary Sciences

Research Article
Adv. Anim. Vet. Sci. 1 (1S): 1 - 3 Special issue-1 (Veterinarians approaches for safeguarding animal health and production)
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Semmannan Kalaiyarasu1*, Mumtesh Kumar Saxena2, Radhe Shyam Gupta3
1Immunology Section, Indian Veterinary Research Institute, Izatnagar, Bareilly, India; 2Animal Biotechnology Centre, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar, India; 3Department of Veterinary Microbiology,College of Veterinary and Animal Sciences, GBPUAT, Pantnagar, India
*Corresponding author:

Salmonella is an important pathogen responsible for food borne illness and other enteric diseases in human and animals. Development of drug resistance in these microbes leads to failure of therapeutic attempts and posing the public health risk. Present study was undertaken to observe the drug resistanance profile of Salmonella typhimurium isolated from different locations of Indian Ganga river. A total of 44 salmonella isolates including 24 S. typhimurium serovars were subjected to antibiogram test by disc diffusion method. The plasmid was isolated and compared with drug resistance pattern to describe its role in resistance mediation. All S. typhimurium serovars were resistant to ampicillin (100%) followed by tetracycline (91.6%), cephatoxime (75%) and nitrofurantoin (66.6%). A few isolates (6.8%) showed resistant to even ciprofloxacin. Gentamicin was the only antibiotic that showed 100% sensitivity to all isolates. Though these isolates showed resistance to most of the commonly used antibiotics, plasmid mediation of drug resistance was not observed. Our study indicates the presence of pathogenic Salmonella serovars in Indian water body and their increasing percentage of multiple drung resistance which is not solely mediated by plasmids.

Key Words: Salmonella typhimurium; Drug resistance; Plasmid; Antibiogram; Ciprofloxacin