Advances in Animal and Veterinary Sciences

Research Article
Adv. Anim. Vet. Sci. 3 (9): 473 - 477
http://dx.doi.org/10.14737/journal.aavs/2015/3.9.473.477
View Full HTML
Download PDF

Amer Murhum Abd AL-Amery

Department of Parasitology, Faculty of Veterinary Medicine, Baghdad University, Baghdad, Iraq.

*Correspondence | Amer Murhum Abd AL-Amery, Baghdad University, Baghdad, Iraq; Email: m.murhum@yahoo.com

Abstract
Aim of this study was to estimate the potential genotoxoicity of sarcocystiosis on cytogenetic of infected ewes lymphocystes by using different cytogenetic test. Forty ewes infected with sarcocystiosis and 20 healthy were collected as an uninfected group. Lymphocytes from peripheral blood of infected and uninfected ewes were used for culture and subsequent cytogenetic studies. Cytogenetic analysis was used as a marker to reflect the genotoxic effect of sarcocystosis parasite on the lymphocytes. The mean Mitotic Index (MI) of infected ewes was significantly lower (P≤ 0.05) than of control group, while mean replicative index (RI) of infected ewes was non-significant as compared with uninfected group. Sister Chromatid Exchange (SCEs) and Chromosomal Aberrations (CAs) showed significant (P≤ 0.05) increase in infected ewes as compared with control group.

Keywords | Sarcocystosis, Cytogenetic analysis, Mitotic index, Replicative index, Chromosome aberration

Editor | Kuldeep Dhama, Indian Veterinary Research Institute, Uttar Pradesh, India.
Received | June 19, 2015; Revised | July 04, 2015; Accepted | July 05, 2015; Published | July 14, 2015

Citation | AL-Amery AMA (2015). Effect of sarcocystosis infection on cytogenetic peripheral blood lymphocytes in ewes. Adv. Anim. Vet. Sci. 3(9): 473-477.

ISSN (Online) | 2307-8316; ISSN (Print) | 2309-3331

Copyright © 2015 AL-Amery. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.