Advances in Animal and Veterinary Sciences

Review Article
Adv. Anim. Vet. Sci. 3 (2S): 73 -84. Special Issue-2 (Reviews on Trends and Advances in Safeguarding Terrestrial /Aquatic Animal Health and Production)
http://dx.doi.org/10.14737/journal.aavs/2015/3.2s.73.84
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Mahmoud Alagawany1*, Mohamed Ezzat Abd El-Hack1, Mayada Ragab Farag2, Ruchi Tiwari3, Kuldeep Dhama4

1Poultry Department, Faculty of Agriculture; 2Forensic Medicine and Toxicology Department, Veterinary Medicine Faculty, Zagazig University, Zagazig 44111, Egypt; 3Department of Veterinary Microbiology, College of Veterinary Sciences, Uttar Pradesh Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwa Vidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura (Uttar Pradesh) – 281001, India; 4Division of Pathology, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243122,Uttar Pradesh, India.

*Correspondence | Mahmoud Alagawany, Zagazig University, Zagazig, Egypt; Email: dr.mahmoud.alagwany@gmail.com

Abstract
The carvacrol compound is an antioxidant nutrient, used to enhance growth and productive performance via modification and activation of gastrointestinal tract structure and function and to inhibit/prevent cancer initiations. Numerous studies performed on animal diets supplemented with phytogenic supplements/feed additives containing natural antioxidants such as carvacrol demonstrated its capability to improve performance indices, feed utilization, immune functions and health of livestock as well as reducing the risks of different animal diseases like cancer and other diseases. Such properties could be due to its ability as antimicrobial, antioxidant, antifungal, immunomodulatory, anticancer and anti-inflammatory agents by preventing free radicals and hazardous compounds from interacting with cellular DNA and its ability to change the gut microflora, improving digestion coefficient and absorption of nutrient compounds. The present review illustrates the chemical and physical proprieties, modes of action, metabolism and excretion, biological properties, natural sources and beneficial aspects of carvacrol in animal and poultry production and health.

Keywords | Carvacrol, Nutrition, Antioxidant, Antimicrobial, Anticancer, Immunity, Health, Production performance, Animal, Poultry, Human