Advances in Animal and Veterinary Sciences

Research Article
Adv. Anim. Vet. Sci. 9(8): 1159-1168
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Elshymaa A. Abdelnaby1, Yara S. Abouelela2*, Noha A. E. Yasin3

1Theriogenology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt; 2Anatomy and Embryology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt; 3Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

Abstract | Canine transmissible venereal tumor (CTVT) is a coitally transmitted neoplasm with the prevalent distribution. This study aimed to compare Doppler changes of internal pudendal (I Pu.A), dorsal (Do Pe. A), and deep penile arteries (De Pe. A) in dogs suffering from TVT and confirm its manner by anatomical vascular segmentation of the penis. Thirty males were categorized into two groups; control groups (Group I, n=17) intact adult healthy dogs of different breeds and TVT affected dogs (Group II, n=13). Diagnosis of TVT was manifested by gross clinical indicators, histopathological, and Doppler examination. All stud dogs were observed by Doppler twice per week for 14 days before and after intravenous treatment by vincristine at a dosage of 0.025 mg/kg body weight. I Pu.A, Do Pe. A and De Pe.A cross-sectional diameters were increased during the first week of infection with a slight increase in the second week, but after treatment, the diameters were showed a consecutive decline in the first two weeks. All arteries Doppler indices were decreased significantly (P ≤ 0.05) in the first and second weeks of infection but in the first week after treatment, the indices were elevated significantly with a marked increase in the second week when compared to normal and to those infected ones. All arteries’ blood flow rate were increased significantly (P ≤ 0.05) in the two weeks of TVT infection, but after vincristine administration, the blood flow rate was significantly decreased. It was concluded that Doppler could be used as a diagnostic tool for dogs suffering from venereal tumors by evaluating the hemodynamic changes in internal pudendal and penile arteries blood flow velocities waveform pattern.

Keywords | Transmissible venereal tumor; Dogs; Doppler; Pudendal artery; Penile artery