Advances in Animal and Veterinary Sciences

Mini Review
Adv. Anim. Vet. Sci. 9(4): 549-554
Http://dx.doi.org/10.17582/journal.aavs/2021/9.4.549.554
View Full HTML
Download PDF

Reham Z. Hamza1,2*, Tarek Al-Talhi4 , Adil A.Gobouri4, Walaa F. Alsanie5, Samy M.El-Megharbel3,4

1Biology Department, College of Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia; 2Zoology Department, Faculty of Science, Zagazig University, Zagazig 44519 , Egypt; 3Chemistry Department , Faculty of Science, Zagazig University, Zagazig 44519, Egypt; 4Chemistry Department, Faculty of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia; 5Department of Clinical Laboratories Science, Faculty of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.

Abstract | Fighting silent killer viruses like SARS-CoV2 is still a real challenge and the recent ability to predict whether human will fight a pandemic remains real challenge, but it is an urgent need to therapeutic strategy due to the appearance of novel deleterious influenza strains to cope with pandemics. The early diagnosis of these killing viruses are considered as very important steps in treatment and alleviating the severe symptoms of SARS-CoV2 viruses. Severe infections may be the cause of death especially due to liver , heart , renal and respiratory failure and in mean times encephalitis due to the severe fever in some cases of COVID-19 and failure of body organ to combat this SARS-CoV2 viral attack and so, we think that vitamin combination with the therapeutic protocol will be of very importance in saving organ vitality. The suggested protocol include treatment with potent anti-viral drugs combination (Favipiravir and acyclovir) which will display on inhibiting of viral RNA and can stop the uncontrolled replication of the virus and then using some potent immunostimulator and immunoprotectant factors like IgG and vitamin.D to provide the body either with ready immunoglobulins or elevate tight junctions of the tissues and improve vitality of the body. So we suggest this therapeutic option that we think it will achieve potent results and clinical trials are recommended to evaluate the efficacy of these drugs combination and their efficacy against COVID-19.

Keywords | SARS-CoV2, Favipiravir, Acyclovir, IgG, Vitamin D, Viral infection, COVID-19.