Advances in Animal and Veterinary Sciences

Case Report
Adv. Anim. Vet. Sci. 8(10): 1045-1049
View Full HTML
Download PDF

Abd Hamid Sifa-Shaida1, Abd Rahaman Yasmin1*, Saulol Hamid Nur-Fazila2, Raslan Ain Fatin2, Wan Noor Ayuni1, Zakaria Alif1, Hasliza Zuhir3

1Department of Veterinary Laboratory Diagnostics, 2Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. 3AZ Animal Clinic and Pet Hotel, 37 Jln Pendidik U1/31, Hicom-Glanmarie Industrial Park, 40150 Shah Alam, Selangor.

Abstract | Feline Infectious Peritonitis (FIP), a fatal disease of cat exists in two major forms namely effusive and noneffusive form. FIP is caused by mutated form of Feline Coronavirus (FCoV) classified under the genus of Alphacoronavirus. Despite common prevalence of FIP in Malaysia, further diagnosis remain challenging due to the complexity of the disease which often required multiple findings to confirm the disease. This case report highlights the progressive wet form of FIP in a male domestic short hair cat named Cromox presented to the Post Mortem Unit, Faculty of Veterinary Medicine, Universiti Putra Malaysia (UPM). Manifestation of distended abdomen, icterus and flu was shown before the cat died. Post-mortem and histopathology analysis of affected organs were performed and since FIP was suspected, RT-PCR against polymerase gene of FCoV was carried out. The post mortem examination revealed generalised icterus at sclera, gums and integuments, straw colour peritoneal fluid and congestion of kidney and liver. Histopathology analysis showed infiltration of mononuclear cells in liver, pulmonary edema and renal desquamation. Meanwhile, RT-PCR and partial sequencing analysis showed evidence of positive Feline Coronavirus which was closely related to the FCoV from China and Netherland. Hence, the cause of death of Cromox was confirmed due to FIP infection. Only supportive treatment can be given to the FIP affected cat since the disease is usually fatal. Vaccination against FIP is not recommended and avoiding the sick cat to share litterbox in the multihousehold cat has been proven to be an effective way to prevent the occurence of FIP.

Keywords | Coronaviridae, Feline infectious peritonitis, Histopathology, Post-mortem, RT-PCR