Advances in Animal and Veterinary Sciences

Research Article
Adv. Anim. Vet. Sci. 8(5): 519-523
Http://dx.doi.org/10.17582/journal.aavs/2020/8.5.519.523
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Aldis Ingrid Rusyawardani1, Widjiati1, Suzanita Utama2, Chairul Anwar1, Lilik Maslachah3, Epy Muhammad Luqman1*

1Department of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga Surabaya, Indonesia – 60115; 2Department of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga Surabaya, Indonesia – 60115; 3Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga Surabaya, Indonesia – 60115.

Abstract | The aim of this research was to analyze the effect of kebar grass on the seminiferous tubules diameter and epithelium thickness of mice exposed to 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). Twenty five BALB/C mice were used with five treatments (4 mice each group): Negative Control (C-), Positive Control (C+) with TCDD 7µg/kgBW IP, and treatment groups that treated with TCDD 7µg/kgBW IP and Kebar Grass orally for 53 days were presented T1 0,045mg/gBW/day, T2 0,080mg/gBW/day, and T3 0,135mg/gBW/day. Results showed that TCDD decreased the diameter and epithelium thickness of seminiferous tubules, while kebar grass extract was proven to maintain diameters but could not maintain epithelium thickness of of the seminiferous tubules.

Keywords | Kebar grass, Seminiferous tubule, Tetrachlorodibenzo-p-dioxin (TCDD), Mice