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Advances in Animal and Veterinary Sciences

Research Article
Adv. Anim. Vet. Sci. 6(11): 492-498
Http://dx.doi.org/10.17582/journal.aavs/2018/6.11.492.498
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Rumiya Tazitdinova1, Raikhan Beisenova2, Gulnur Saspugayeva2, Bakhyt Aubakirova2, Zina Nurgalieva2, Amanbek Zandybai2, Idiya Fakhrudenova1, Aigul Kurmanbayeva1

1Sh. Ualikhanov Kokshetau State University, Kazakhstan, 020000, Kokshetau, Abay Str., 76; 2L.N. Gumilyov Eurasian National University, 010000, Astana, Satpayev Str., 2, Kazakhstan.

Abstract | The accelerated growth rates of cities, industrial development and mineral extraction have led to an increase in the volume of heavy metals entering the environment. The impact of heavy metals has been studied by many scientists, but there are still limited data on the complex effect of various heavy metals. Therefore, currently, there is an increasing interest in the effect of several heavy metals on living organisms. In this research, we modeled the chronic effects of three groups of heavy metals on the body of rats, as well as determined their biochemical parameters and changes in comparison with the control group. The results of our studies have shown that when combined with chronic intoxication with heavy metal salts, the biochemical indices of blood may vary, which is caused by a violation of the functions of the liver, kidneys, and heart muscle. Against the background of the toxic effects of heavy metals, we used “Ursodex” and “Schrot Rastoropshy” as helpful drugs for the organism, which contributed to a decrease in the toxicity of metals. The level of the negative effect of these elements on the biochemical indices of the blood of experimental animals decreased.

Keywords | Heavy metals, Intoxication, Rat blood, Blood counts, Biochemical analysis, Biochemical indices