Research Journal for Veterinary Practitioners

Research Article
Res J. Vet. Pract. 9(2): 12-17
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Camilo Romero Núñez1*, Rafael Heredia Cárdenas1, Laura Miranda Contreras1, Galia Sheinberg Waisburd2, Alberto Martin Cordero3

1Dermavet Hospital Veterinario, José de la Luz Blanco, Mz. 187, Lt. 33, Col. Santa Martha Acatitla, Ciudad de México; 2Centro Veterinario México, Calle Cincinnati #22, Benito Juárez, Ciudad de los Deportes, 03710 Ciudad de México, México; 3Vetderm Dermatología Veterinaria Especializada Av Niños Héroes 1665, Guadalajara, México.

Abstract | There is a new class of insecticides/acaricides—isoxazolines—that shows good efficacy against several ectoparasites. Sarolaner belongs to this family of molecules, and its potency, safety and pharmacokinetics have been optimised for use in dogs and cats. Furthermore, it presents significant selectivity for insect neurons. Nevertheless, its negative effects on susceptible non-target microorganisms like earthworms (which can be indirectly affected by insecticides) are unknown. The present study examined the effect of sarolaner on earthworms via two methods. In the first experiment, faeces were collected from 24 rabbits, 18 of which were medicated with sarolaner. The faeces were applied to a compost with earthworms. In the second experiment, sarolaner was applied directly to the earthworms. For both experiments, the number of earthworms was evaluated on days 1, 15 and 30 post-treatment. There were no significant differences between the sarolaner-treated and control groups at 15 and 30 days. Thus, sarolaner exhibited no negative effects with regards to earthworm survival. 

Keywords | Earthworm, Evaluation, Sarolaner, Toxicity