Research Journal for Veterinary Practitioners

Research Article
Res J. Vet. Pract. 9(1): 1-8
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Gaadee H. I. M1*, Gehan M. S2

1First Researcher. Biochemistry Unit, Agriculture Research Center (ARC), Animal Health Research Institute;
2First Researcher, Parasitological Unit, Agriculture Research Center (ARC). Animal Health Research Institute.

Abstract | Pregnancy toxemia is a common problem that occurs due to an imbalance between energy requirements in pregnant Ovis aries and the energy provided by the diet consumed. The study was carried on 45 Ovis aries reared under the same living and weather conditions and classified into three groups according to pregnancy and healthy state (group A)., pregnancy with more than on fetus and suffering from clinically pregnancy toxemia, (group B)., pregnant with more than one fetus and clinically healthy and (group C)., non-pregnant and clinically healthy and used as a control. The aim of the study was to evaluate the role of nutritional disorders in initiating the process of pregnancy toxemia in Ovis aries and the associated clinical, biochemical and hematological changes that occur with this disorder, pregnancy toxemia in Ovis aries diagnosed by clinical signs and confirmed by evaluated β-hydroxybutyrate level by chemical and urinalysis. Clinical examination was performed to record clinical changes associated with the disease, two types of blood sample collected for hematological and biochemical studies, where biochemical parameters as glucose, cholesterols, albumin, total protein levels were found statistically lower (P<0.05), in group A than B, C groups, while triglyceride, ALT and AST were found a significant increase in group A than B,C groups. Also MDA as oxidative stress parameter was found significant higher (P<0.05), while cocktails and GSH were considerably decreased, while hematological analysis revealed that erythropenia, oligochromenia, reduced hematocrit, leukocytosis and lymphocytosis in group (A and B).

Keywords | Ovis aries, Sheep, Pregnancy toxemia, Metabolic disorders, Oxidant, Antioxidant response.