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Research Journal for Veterinary Practitioners

Research Article
Res. J. Vet. Pract. 6(3): 20-25
Http://dx.doi.org/10.17582/journal.rjvp/2018/6.3.20.25
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Soontaree Petchdee1*, Aree Laikul1, Juthamas Leklub2, Jutamat Rattanakunuprakarn2

1Department of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen Campus 73140, Thailand; 2KasetsartUniversity Veterinary Teaching Hospital Kamphaeng Saen campus, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen Campus, 73140, Thailand.

Abstract | The objective of this study was to identify the effects of combined anesthetic drugs on heart rate variability (HRV), respiratory function and recovery behavior in horses. Eight healthy Thai native crossbred horses were enrolled in this study. Horses were premedicated and induction with 2 protocols, protocol 1; acepromazine (0.04mg/kg)+ xylazine (1 mg/kg)+ ketamine (2.2 mg/kg) and protocol 2; detomidine (5 mcg/kg)+ketamine (2.2 mg/kg). Heart rate and heart rate variability of 8horses were measured 20 minutes before and after administered the anesthetic drugs. Doppler was used to obtained systolic, diastolic and mean blood pressures. After anesthetic drug administration, horses premedicated and induction with acepromazine, xylazine and ketamine had the lower HR values when compared with another protocols. The HRV low frequency (LF) and high frequency (HF) powers ratio increased in horses premedicated and intubation with detomidine and xylazine. The marked hypoventilation were observed after anesthetic drugs administration in both groups. There were only minimal differences in the quality of recovery. However, overall of recovery scores were higher in group of protocol 1. This study demonstrated that acepromazine + xylazine + ketamine preserved the cardiovascular function and safe to use for the surgical applicability in horses.

Keywords | Anesthesia, Horse, Autonomic nervous activity, Heart rate variability, Echocardiography