Advances in Animal and Veterinary Sciences

Research Article
Adv. Anim. Vet. Sci. 7(s1): 40-44
Http://dx.doi.org/10.17582/journal.aavs/2019/7.s1.40.44
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Nikolay Vasilievich Vinokurov*, Evgeniy Semenovich Sleptsov, Ayal Ivanovich Stepanov, Valeriy Innokentievich Fedorov, Nikolay Spiridonovich Robbek, Galina Ivanovna Dayanova, Ayal Alekseevich Ivanov

Federal State Budgetary Scientific Institution “Yakut Research Institute of Agriculture named after M.G. Safronov”, Bestuzhev-Marlinsky Street 23/1, 677001, Yakutsk, Russia

Abstract | The research was aimed at studying the biological properties of the vaccine from strain Brucella abortus strain 75/79-AB in reindeer. Here we describes a series of experiments on the reactogenic properties of a weakly agglutinogenic vaccine from strain B. abortus 75/79-АВ. The spread rate and colonization rate of a culture from strain B. abortus 75/79-AB in the animal organisms were studied based on the dosage of the preparation. Analysis of the results of the experiment for studying the immunological reactivity of animals after the administration of various dosages of the vaccine from strain B. abortus 75/79-AV shows that there is some dependence of the level of specific antibodies in the blood serum of reindeer on the dosages of the vaccine used. The results of the research show that the experimental animals inoculated with this strain were able to resist experimental infection with the reference culture B. abortus 1330. The dynamics of antibody titers after the administration of the vaccine from strain B. abortus 75/79-AV are the evidence of the fact that this strain is actually weakly agglutinogenic, and diagnostic titers fall out after 70 days in the blood serum of the vaccinated reindeer.

Keywords | Brucellosis, Vaccine, Strain, Reindeer, Antibodies, Immunogenicity, Immune reactivity