Figure 5
Sections of rat testis stained with Hematoxylin and Eosin revealed the effect of 6MP and TQ in histological architecture of testicular tissues. Testis of control rats (a, b) and (TQ) Thymoquinone (c, d) shows the normal histological appearance of testis , testis of (6MP) 6-mercaptopurine treated rats (e,f) shows narrowing of seminiferous tubules, widening in interstitial spaces, few spermatozoa, germ cell degeneration. Testis of (TQ+6MP) co-administration of TQ and 6MP (g,h) shows almost normal architecture, spermatozoa and Leydig cells are histologically normal, and normal morphology of seminiferous tubules was observed.