Effect of C. limon and C. paradisi fruit peel hydroethanolic extracts on right hind paw circumference at tarsal pad in arthritic rats. Means, which share the same superscript symbol(s), are not significantly different. 

Effect of C. limon and C. paradisi fruit peel hydroethanolic extracts on volume of right hind paw (cm3) in arthritic rats. Means, which share the same superscript symbol(s), are not significantly different. 

Effect of C. limon and C. paradisi fruit peel hydroethanolic extracts on right hind paw thickness in arthritic rats. Means, which share the same superscript symbol(s), are not significantly different. 

Effect of C. limon and C. paradisi fruit peel hydroethanolic extracts on right hind leg ankle joint COX-1 expression relative to β-actin in CFA-induced arthritic rats. Means, which share the same superscript symbol(s), are not significantly different.
Top: Gel photograph depicting COX-1 and β-actin PCR products
Bottom: Corresponding intensity analysis of right ankle joint COX-1 PCR products from 3 different experiments, represented as the COX-1 mRNA percentage of β-actin mRNA. 

Effect of C. limon and C. paradisi fruit peel hydroethanolic extracts on right hind leg ankle joint IL-1β expression relative to β-actin in CFA-induced arthritic rats. Means, which share the same superscript symbol(s), are not significantly different.
Top: Gel photograph depicting IL-1β and β-actin PCR products
Bottom: Corresponding intensity analysis of right ankle joint IL-1β PCR products from 3 different experiments, represented as the IL-1β mRNA percentage of β-actin mRNA. 

Effect of C. limon and C. paradisi fruit peel hydroethanolic extracts on right hind leg ankle joint IL-6 expression relative to β-actin in CFA-induced arthritic rats. Means, which share the same superscript symbol(s), are not significantly different.
Top: Gel photograph depicting IL-6 and β-actin PCR products
Bottom: Corresponding intensity analysis of right ankle joint IL-6 PCR products from 3 different experiments, represented as the IL-6 mRNA percentage of β-actin mRNA. 

Effect of C. limon and C. paradisi fruit peel hydroethanolic extracts on right hind leg ankle joint IL-4 expression relative to β-actin in CFA-induced arthritic rats. Means, which share the same superscript symbol(s), are not significantly different.
Top: Gel photograph depicting IL-4 and β-actin PCR products
Bottom: Corresponding intensity analysis of right ankle joint IL-4 PCR products from 3 different experiments, represented as the IL-4 mRNA percentage of β-actin mRNA. 

Photomicrograph of a section in ankle joint of rat; 8: normal group after 9 days, 9: normal group after 18 days, 10: arthritic control group after 9 days, 11a-c: arthritic control group after 18 days, 12: arthritic group treated with C. limon fruit peel after 9 days, 13: arthritic group treated with C. limon fruit peel after 18 days, 14 a-b: arthritic group treated with C. paradisi fruit peel after 9 days, 15: arthritic group treated with C. paradisi fruit peel after 18 days ( H & E X 100). 

Photomicrograph of; 16: section in spleen of rat from normal group after 9 days, 17: section in spleen of rat from normal group after 18 days, 18 a-c: sections in spleens of rats from arthritic control group after 9 days, 19 a-c: sections in spleens of rats from arthritic control group after 18 days, 20: spleen of rat from arthritic group treated with C. limon fruit after 9 days, 21: spleen of rat from arthritic group treated with C. limon peels after 18 days, 22: spleen of rat from arthritic group treated with C. paradisi peels after 9 days, 23: spleen of rat from arthritic group treated with C. paradisi peels after 18 days,24 a-b: sections in thymus of rats from normal group after 9 days of normal rats, 25 a-b sections in thymus of rats from normal group after 18 days of normal rats, 26: thymus of rats from arthritic control group after 9 days, 27 a-b: sections thymus of rats from arthritic control group after 18 days, 28: section in thymus of rat from arthritic group treated with C. limon peel extract after 9 days, 29: section in thymus of rat from arthritic group treated with C. limon peel extract after 18 days, 30: section in thymus of rat from arthritic group treated with C. paradisi fruit peels after 9 days and 31: section in thymus of rat from arthritic group treated with C. paradisi fruit peels after 18 days.