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Journal of Infection and Molecular Biology

Research Article
J. Inf. Mol. Biol. 2 (3): 35 - 38
http://dx.doi.org/10.14737/jimb.2307-5465/2.3.35.38
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Abdul Basit*, Kashif Rahim, Iqbal Ahmad, Mehwish Shafiqe, Sameerah Mushtaq, Humera Shaheen, Ilyas Khan.
Department of Microbiology, Kohat University of Science and Technology (KUST), Khyber PakhtunKhwa, 26000, Pakistan
*Corresponding author: aabdul.9090@gmail.com

ABSTRACT
Hepatitis is major important global health problem especially in developing countries. Hepatitis B (HBV) and hepatitis (HCV) are becoming endemic for entire world. Patients with HBV and HCV are at great threat for increasing chronic liver diseases. The present study was carried out to estimate the prevalence of HBV and HCV in hospital patients of Pakistan Institute of Medical Sciences, Islamabad (PIMS). A total of 845 patients were screened for hepatitis over the period of three months (1st June to 31st August 2011). All patients underwent screening for HB–Ag and anti–HCV antibodies by ELISA. The overall prevalence of HBV and HCV was found to be (2.8%) and (18.9%) respectively. Moreover Co–infection (both HBV and HCV) was found to be (0.7%). High prevalence was found in males (24%) followed by females (20.3%) with statistically significant association (P = 0.0217) [OR=0.85 (CI = 0.6–1.17)]. Similarly, HBV and HCV were found to be more common among married individuals (23.1%) compared to un–married (20.7%) (P = 0.1675) [OR = 0.89 (CI = 0.62– 1.27)]. Furthermore, the higher prevalence of HBV and HCV was recorded in patients with age group of greater than 60 years (57.2%) [OR = 0.39 (CI= 0.29 – 0.53)] followed by age group of 40–60 years (18.3%) [OR = 1.2 (CI = 0.9– 1.6)]. Significance association was found among the age groups (P = 0.0231). In conclusion, the present study provides the preliminary information about HBV and HCV prevalence due to lack of public health awareness on transmission of disease. More sensitive methods for detection of hepatitis virus, management and control to overcome its future spread are required. It is recommended that public health authorities should educate the general public regarding prevention.

Key Words: Hepatitis B, Hepatitis C, ELISA, PIMS Islamabad