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Journal of Animal Health and Production

Research Article
J. Anim. Health Prod. 5(3): 107-114
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Zongo André1,4, Kaboré Adama1*, Bengaly Zakaria2, Vitouley Sèna Hervé2, Traoré Aristide3, Tamboura Hamidou Hamadou1, Belem Adrien Marie Gaston4

1Département Productions Animales / Institut de l’Environnement et de Recherches Agricoles (INERA), 04 BP 8645 Ouagadougou 04, Burkina Faso; 2Centre International de Recherche-Développement sur l’Elevage en zone Subhumide (CIRDES), 01 BP 454 Bobo-Dioulasso 01, Burkina Faso; 3Institut de Recherche en Sciences de la Sante (IRSS/CNRST) 01 BP 7192 Ouagadougou 01 Burkina Faso; 4Institut du Développement Rural (IDR)/Université Nazi Boni, 01 BP 3770 Ouagadougou 01, Burkina Faso, West Africa.

Abstract | In the pastoral zone of Gaongho in Burkina Faso, the main disease of ruminants is the African Animal Trypanosomiasis (AAT) which is very often controlled by herders with the aqueous extracts of five plants whose present study proposes to evaluate the potential trypanocidal activities. To this end, a parasitological field survey in ruminants was carried out followed by an in vitro trypanocidal test of five plant extracts using three concentrations (25, 50 and 100 mg / ml) in triplicate in comparison with negative (PBS) and positive (Veriben) controls in the laboratory. The field survey revealed an overall prevalence rate of 4.14% for trypanosomes, including 4.54% for cattle and sheep and 3.33% for goats, with no significant difference (P ˃ 0. 05) was recorded between the three ruminant species. Among the latter, the sex effect showed a significant difference in goats where males were more infested (P = 0.0015) than females. On the other hand, the age of the animals presented no significant difference (P = 0.8218) between the three species. All ruminants tested were more infested with Trypanosoma brucei brucei (66.67%) than T. congolense (33.33%). The in vitro test was conducted with aqueous extracts of five plants (Balanites aegyptiaca, Capparis sepiaria, Guiera senegalensis, Mitragyna inermis, and Vitellaria paradoxa) on Trypanosoma brucei brucei. Concentrations of 50 and 100 mg / ml of G. senegalensis leaf extracts and V. paradoxa bark caused high mortality of T. brucei brucei and were comparable to Veriben, the standard reference product. The results obtained with the extracts of G. senegalensis and V. paradoxa showed that these plantsmay be the potential source of trypanocidal drugs.

Keywords | In vitro, Prevalence; Trypanocidal activity, Medicinal plants, Gaongho pastoral area​​, Burkina Faso