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Journal of Animal Health and Production

Review Article
J. Anim. Health Prod. 4(4): 140-144
Http://dx.doi.org/10.14737/journal.jahp/2016/4.4.140.144
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Iqra Bano, Hira Sajjad, Ali Mujtaba Shah, Ambreen Leghari, Khalid Hussain Mirbahar, Sheeba Shams, Munaza Soomro

1Departememt of Physiology and Biochemistry, Faculty of Bio-Sciences, Shaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand, Sindh, Pakistan; 2Key Laboratory Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, Huazhong Agricultural University, Wuhan, Hubei 430070, People’s Republic of China; 3Shaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand, Sindh, Pakistan; 4Sindh Agriculture University, Tandojam, Sindh, Pakistan.
 
Abstract | The rabies is an infectious disease, which defects brain caused by the virus known as lyssavirus belonging to family Rhabdoviridae. It is a semi zoonotic acute disease because the rabid animal dies after illness. It is transmitted by all homoeothermic animals and virus is secreted in the saliva of an infected animal. However, dogs are considered as high risk while in America, bat bites are also the cause of spread of rabies. The incubation period of this disease is approximately up to six months long or in some cases, it is short up to just four days. Symptoms are produced after completion of the incubation period. The virus gets entrance in the brain and causes damage there, after that it moves toward salivary gland in order to transmit in other animals while biting or due to contamination of saliva of an infected animal. The clinical signs and symptoms of this disease could be confused with some other diseases such as polio, tetanus, and botulism. Hence, confirmatory diagnosis is done by using techniques including polymerase chain reaction, direct fluorescent antibody test, and mouse inoculation technique. This paper reviews the transmission, pathogenesis, control, prevention and treatment of rabies since it is a highly fatal disease so preventive measures could be taken to fight against this infection.

Keywords | Rabies, Transmission, Treatment, Control, Review