Journal of Animal Health and Production

Research Article
J. Anim. Health Prod.1 (2): 15 - 19
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Subhash Mailk, Amit Kumar*, Amit Kumar Verma, Manoj Kumar Gupta, Som Dutt Sharma, Arvind Kumar Sharma, Anu Rahal
Uttar Pradesh Pandit Deen Dayal Uphadhayay Veterinary University Evam Go Anusandhan Sansthan, Mathura, UP, India, 281001
*Corresponding Author: smalikduvasu2008@gmail.com

ABSTRACT
Diarrhea in farm animals, especially in neonatal calves is one of the most challenging clinical syndromes encountered by practicing large animal’s veterinary practitioners throughout the world. Therefore looking into the intricacy of early age calf diarrhea primarily due to E. coli, the present study was designed to perform the isolation and identification of involved E. coli strains in calf diarrhea and also to establish their drug sensitivity pattern. During the study period total 109 faecal samples were collected from diarrheic cattle and buffalo calves less than three months of age from the university teaching veterinary clinics complex, DUVASU, Mathura, University dairy farm, nearby gaushalas located at Vrindavan and Mathura along with the Veterinary Hospitals of western Utter Pradesh located in district Muzaffarnagar, Baghpat, Meerut, Gautambudh Nagar, Ghaziabad and Saharanpur. After laboratory confirmation out of 109 processed samples, only 41 were positive for E. coli. Out of these 41 isolates only 13 revealed the toxin production, hence were pathogenic. On the basis of drug sensitivity test, Amikacin (87.80% sensitivity), Aztreonam (73.17%) and Gentamicin (51.21%) were found to be the effective drugs which could prohibit the growth of E. coli isolates obtained during sudy. However, the presence of 100% resistance against Ampicillin, Cefdinir, Co-trimoxazole, Cloxacillin, Erythyromycin, Lincomycin, Penicillin, Rifampin, Tetracyclin and Vancomycin is matter of concern particularly the resistance against Norfloxacin and Pefloxacin as fluroquinoles are very commonly used in cases of gastroenteritis.

Key Words: Incidence, Drug resistance pattern, Collibacillosis, Calves, Utter Pradesh, India