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Journal of Animal Health and Production

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Umar Bacha1*, Muhammad Nasir1, Muhammad Asif Ali1, Javed Muhammad2, Ali Ahmad Sheikh2

1Department of Food Science & Human Nutrition, University of Veterinary & animal Sciences, Lahore, Pakistan; 2University Diagnostic laboratory, University of Veterinary & Animal Sciences, Lahore, Pakistan;
*Corresponding Author: bacha.umar474@gmail.com

Journal of Animal Health and Production. 1 (1): 1–5

ABSTRACT
Nucleotides being novel substances act as prebiotic and; in most cases regulate function of gastro intestinal tract (GIT). They immensely regulate genes expression of immune cells, relieving stress, execute neurodevelopment and inhibit apoptosis. More so, they take part in oxido-reduction process, propagate cell signaling and regulate cell cycle of mammalian cells. Based on these important functions, European commission permitted the use of certain nucleotides in preparation of infant foods. However, nucleotides inclusion in the diet has to be elucidated for clinical significance particularly a threshold level of nucleotides inclusion has to be find out. Where levels of polyunsaturated fatty acid (PUFA) may not exceeds than monounsaturated fatty acid (MUFA) because of adverse effect associated with PUFA. Studies have shown promising results regarding elongation and concentration of various fatty acids. But still there is need to determine whether this effect may or not produce oxidative stress because optimum level of fatty acid is necessary to avoid stress particularly in animals.

Key Words: Nucleotide supplementation, Diet, Immunity, Yeast, Functional food