Figure 3
Testicular histopathology in rats treated with quercetin and vanadium pentoxide (VP). Photomicrographs of testicular sections. Control group (A &B), quercetin group (C&D), VP treated-group (E &F), quercetin +VP treated-group (G&H). B, D, F, H represents higher magnifications of the boxed area in A, C, E, and G, respectively. The control and quercetin-treated rats (A, B, C, and D) showed normal histological structures of closely packed seminiferous tubules (ST) lined with seminiferous epithelial cells (SE), and interstitial tissue containing Leydig cells (solid arrows). The VP-treated group (E and F) showed severe germinal epithelial atrophy (dashed arrows), with interstitial tissue replaced with homogenous eosinophilic materials (asterisk) and vacuoles (arrowheads). VP-induced abnormalities were less evident in the VP and quercetin co-treated group (G and H). Scale bars A,C, E; 200 µm , B,D,F 50 µm.